![]() ![]() Anastomosing vascular channels are focally observed. A, Poorly differentiated angiosarcoma shows spindle tumor cells with solid and fascicular growth patterns. B, The tumor cells show nuclear staining for human herpesvirus 8 (hematoxylin-eosin, original magnification ×200 original magnification ×200 ).įigure 6 Angiosarcoma. Intracytoplasmic hyaline globules (arrow) are present. Intervening slitlike or sievelike spaces contain erythrocytes. ![]() A, The tumor is composed of cellular, uniform spindle cells arranged in a fascicular pattern. Nuclear atypia and frequent mitoses are present (hematoxylin-eosin, original magnifications ×1 and ×200 ).įigure 5 Kaposi sarcoma. B, The tumor cells have elongated, blunt-ended nuclei and brightly eosinophilic cytoplasm, and are arranged in a fascicular pattern. A, Scanning magnification shows an ill-defined, infiltrative tumor in the dermis, with superficial subcutaneous extension. 1– 3 Kaposi sarcoma is among the most common cutaneous soft tissue sarcomas in the United States. Common vascular neoplasms include Kaposi sarcoma (KS) and angiosarcoma. The common primary cutaneous sarcomas include dermatofibrosarcoma protuberans (DFSP), leiomyosarcoma, and pleomorphic dermal sarcoma (PDS) (also known as an aggressive variant of atypical fibroxanthoma ). Cutaneous soft tissue sarcomas represent less than 1% of malignant tumors. Fibrous histiocytoma (FH also known as dermatofibroma) is one of the most common cutaneous mesenchymal neoplasms. Benign lesions are more common than malignant tumors. The approach used for the diagnosis of these tumors should be based on knowledge of the relative frequencies of different tumor types, appropriate consideration of clinical context, and correct interpretation of histologic features. Cutaneous spindle cell lesions encompass a heterogeneous group of tumors that range from reactive to benign, borderline, and malignant tumors. ![]()
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